Abstract Background Protein-DNA interaction governs a large number of cellular processes, and it can be altered by a small fraction of interface residues, i.e., the so-called hot spots, which account for most of the interface binding free energy.Accurate prediction of hot spots is critical to understand the principle of protein-DNA interactions.The
Abstract Cancer has always been a worldwide problem, and the application of radiotherapy has greatly improved the survival rate of cancer patients.Radiotherapy can modulate multiple cell fate decisions to kill tumor cells and achieve its marigold velvet curtains therapeutic effect.With the development of radiotherapy technology, how to increase the
Background: sww x Depressive symptoms are common among post myocardial infarction (MI) patients and may cause negative impacts on cardiac prognosis.35 to 45% of MI patients report depression.Depression is an independent risk factor for MI and post MI mortality and decreased quality of life in post MI patients.The link between depression and MI is b
Many classifications of hypospadias have been published, mainly based on the position of the ectopic meatus, which is an insufficient criterion to define the severity of this malformation.What really marks the proximal landmark of this malformation is the level of division of the corpus spongiosum, which is always proximal to the ectopic meatus.In
Association mapping is a powerful approach to detect associations between traits of interest and genetic markers based on linkage disequilibrium in molecular plant breeding.The aim of this study was the identification of single nucleotide polymorphisms (SNPs) and SilicoDArT markers associated with yield traits and morphological features in maize.Pl